Knockdown Rate of Sheep Lice Exposed to Spinosad

Rate of knockdown in sheep lice exposed to spinosad (40mg/L)1

Knockdown Rate of Sheep Lice Exposed to Spinosad

^40 mg/L was the minimum concentration of spinosad required in a lab study to kill 100% of a fully susceptible lice strain

STARTS KILLING LICE WITHIN HOURS

Extinosad Pour-On contains the active ingredient, spinosad, which provides rapid knockdown control of lice, including adults and nymphs. A laboratory study found spinosad started killing lice within hours of exposure, with 70% of exposed lice 'knocked down' or dead within 4 hours. This figure increased to 98% within 8 hours. All adult and nymphal lice were dead within 24 hours of contact.¹
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Unique mode
of action

Extinosad Pour-On has a unique mode of action.² Upon contact or ingestion, spinosad causes involuntary and prolonged tremors in the nervous system of target species, leading to irreversible paralysis and death. Rotation between products with different modes of action may prolong the effective life of all available treatments.³
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No Known Field Resistance

Extinosad Pour-On is a member of the spinosyn chemical group, which is unrelated to any other chemical group used for the control of sheep lice. Its unique mode of action kills strains of lice that are resistant to synthetic pyrethroids.¹ No field strains of lice resistant to spinosad have been identified in Australia, so you can have complete confidence that Extinosad Pour-On will provide effective lice control.
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Control That Goes
The Distance

Extinosad Pour-On provides effective lice control when applied off-shears. Extensive research and commercial experience have confirmed no lice will be detected for a minimum of 20 weeks after application off-shears in accordance with label directions.⁴ These trials confirm Extinosad Pour-On controls any nymphs emerging from eggs that can hatch up to 14 days after treatment.
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6 Month Off-Shears Guarantee*

Elanco guarantees that when Extinosad Pour-On is applied correctly to sheep off-shears, there will be no detectable lice present on sheep six months after treatment. *To qualify, simply register your purchase within 14 days of application and apply Extinosad Pour-On in accordance with the label directions.
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Maximum
Flexibility

Extinosad Pour-On can be applied up to seven days off-shears or to sheep with long wool. It has no withholding period for wool and an Export Slaughter Interval (ESI) of only 21 days when applied off-shears and to suckling lambs (unshorn), giving you maximum flexibility in your management and marketing options.
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Good Management Practices

Good management is essential to ensuring sheep remain lice free through to the next shearing Read More
Blue Check Treat all sheep on the property at the same time. Avoid split shearing
Blue Check Muster each paddock thoroughly to ensure all sheep are treated
Blue Check Conduct a second muster if necessary
Blue Check Check boundary fences to prevent untreated or lice-infested sheep from joining treated mobs
Blue Check Do not mix treated sheep with untreated sheep, infested sheep or those of unknown lice status
Blue Check Ensure sheep are cleanly shorn. Grass seeds, lumpy wool or flystrike can hinder shearing and may impede the spread of Extinosad Pour-On
Blue Check Sheep that require treatment with a long wool lousicide should be retreated with an off-shears lousicide at the next shearing
Blue Check Avoid treating ewes within six weeks of the commencement of lambing, as live lice may infest the lambs from these ewes (off-shears recommendation)
Blue Check If ewes have lambs at foot at shearing time, ensure either that the unshorn lambs are treated at the suckling lamb (unshorn) dose rate or shear the lambs and treat using the off shears dose rate table
Practices for Sheep to Remain Lice Free

References: 1. Levot, G. (2008). Speed of action and in vitro efficacy of spinosad against sheep body lice, Bovicola ovis (Schrank) (Phthiraptera: Trichodectidae), resistant to pyrethroid, organophosphate or insect growth regulator insecticides. Aust. J Entomol. 47:251-255. 2. Cisneros, J et al. (2002). Toxic effects of spinosad on predatory insects. Biol. Control 23:156-163. 3. James, P. (2013). Preventing resistance in sheep lice, www.liceboss.com.au (AWI, Sheep CRC). 4. Elanco data on file. Part 8 Efficacy and Safety Summary from the Submission dossier to the APVMA.